Si toma diazepam junto con otros medicamentos para controlar las convulsiones, no deje de tomar diazepam sin consultarlo antes con su médico, incluso si experimenta efectos secundarios como cambios inusuales en el comportamiento o estado de ánimo.
Active metabolites: N-desmethyldiazepam and temazepam, which might be the two even more metabolized to oxazepam; largely eradicated by glucuronidation
If you're taking far too much VALIUM, call your healthcare supplier or check out the nearest clinic emergency room at once.
Propylene glycol toxicity described in patients addressed with diazepam injection at doses substantially higher than advised when it had been being used to take care of Alcoholic beverages withdrawal signs or symptoms at doses >900 mg/working day Propylene glycol toxicity is linked to an anion hole metabolic acidosis, serum hyperosmolality, and greater lactate
diazepam and daridorexant equally increase sedation. Modify Therapy/Check Intently. Coadministration raises threat of CNS melancholy, which may lead to additive impairment of psychomotor general performance and result in daytime impairment.
巴比妥类药物(比如:苯巴比妥) • 苯二氮平類藥物(比如:地西泮) • 氨己烯酸,及托吡酯
Prior to deciding to choose VALIUM, inform your Health care provider about all your healthcare circumstances, which includes in case you: have or have had depression, mood issues, or suicidal thoughts or actions
Neonatal withdrawal syndrome and signs and symptoms suggestive of floppy infant syndrome connected with administration of benzodiazepines over the later levels of pregnancy and peripartum period of time are reported Benzodiazepines cross the placenta and could deliver respiratory despair, hypotonia, and sedation in neonates; keep an eye on neonates exposed to therapy during pregnancy or website labor for signs of sedation, respiratory melancholy, hypotonia, and feeding issues; observe neonates exposed to therapy during pregnancy for signs of withdrawal; regulate these neonates accordingly Animal facts
lorlatinib will lessen the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
dexamethasone will lessen the level or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
eslicarbazepine acetate will increase the amount or influence of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of.
Minor improvements in EEG patterns, usually lower-voltage rapidly activity, are already noticed in clients all through and right after diazepam therapy and so are of no known importance
nifedipine will increase the amount or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Watch for signs of urinary retention or minimized gastric motility if oliceridine is coadministered with anticholinergics.